2770246-77-8
2770246-77-8
Chemical Structure
HSD17B13-IN-52
- CAS No.: 2770246-77-8
- Formula:C26H22Cl2N4O4
- Molecular Weight:525.38
InChIKey: WZDQFKAHFLUNMB-UHFFFAOYSA-N
SMILES: O=C(C1=CC(Cl)=C(C(Cl)=C1)O)NC2=CC=CC(N=CN3CC4=C(N5CCOCC5)C=CC=C4)=C2C3=O
Biological Activity: HSD17B13-IN-52 (Compound 84) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-52 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
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HSD17B13-IN-52 | HSD17B13-IN-52 (Compound 84) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-52 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI). | |||||||||||||||||||||
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