2797225-47-7
Chemical Structure
PfGSK3/PfPK6-IN-2
- CAS No.: 2797225-47-7
- Formula:C24H25Cl2N5OS
- Molecular Weight:502.46
IUPAC Name: (4-((5-chloro-4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)amino)phenyl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanone
InChIKey: SZKUPGRFEZHAPU-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(NC2=NC=C(Cl)C(C3=CC=C(Cl)S3)=N2)C=C1)N4CCC(N5CCCC5)CC4
Biological Activity: PfGSK3/PfPK6-IN-2 is a potent dual PfGSK3/PfPK6 (Plasmodium falciparum GSK3/PK6) inhibitor (IC50: 172 nM and 11 nM respectively). PfGSK3/PfPK6-IN-2 can be used in the research of Malaria[1].
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PfGSK3/PfPK6-IN-2 | PfGSK3/PfPK6-IN-2 is a potent dual PfGSK3/PfPK6 (Plasmodium falciparum GSK3/PK6) inhibitor (IC50: 172 nM and 11 nM respectively). PfGSK3/PfPK6-IN-2 can be used in the research of Malaria. | |||||||||||||||||||||
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Keywords