2813347-44-1
2813347-44-1
Chemical Structure
ZLWT-37
- CAS No.: 2813347-44-1
- Formula:C26H30ClN5O
- Molecular Weight:464.00
IUPAC Name: (S)-N-(4-(9-(3-aminopyrrolidin-1-yl)-5,6,7,8-tetrahydroacridin-2-yl)pyridin-2-yl)cyclopropanecarboxamide hydrochloride
InChIKey: AZCMSSLJXPAIPL-FYZYNONXSA-N
SMILES: N[C@H]1CCN(C1)C2=C3CCCCC3=NC4=C2C=C(C=C4)C5=CC=NC(NC(C6CC6)=O)=C5.Cl
Biological Activity: ZLWT-37 is a potent, orally active CDKs inhibitor with IC50 values of 0.002 μM and 0.054 μM against CDK9 and CDK2, respectively. ZLWT-37 induces apoptosis and arrests the cell cycle in the G2/M phase in HCT116 cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
ZLWT-37 | ZLWT-37 is a potent, orally active CDKs inhibitor with IC50 values of 0.002 μM and 0.054 μM against CDK9 and CDK2, respectively. ZLWT-37 induces apoptosis and arrests the cell cycle in the G2/M phase in HCT116 cells. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
