2834087-69-1
Chemical Structure
HIV-1 inhibitor-50
- CAS No.: 2834087-69-1
- Formula:C24H18FN5O2
- Molecular Weight:427.43
IUPAC Name: (E)-4-((4-(4-(2-cyanovinyl)-2,6-dimethylphenoxy)-5,7-dihydrofuro[3,4-d]pyrimidin-2-yl)amino)-2-fluorobenzonitrile
InChIKey: NXWBHECFJJKVHJ-ONEGZZNKSA-N
SMILES: CC1=C(OC2=C3COCC3=NC(NC4=CC(F)=C(C=C4)C#N)=N2)C(C)=CC(/C=C/C#N)=C1
Biological Activity: HIV-1 invistor-50 is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that targets HIV-1 reverse transcriptase (RT) (IC50=50 nM). HIV-1 inhibitor-50 shows significant antiviral activity, with EC50s of 2.22-53.3nM against HIV-1 IIIB and its mutant strains[1].
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HIV-1 inhibitor-50 | HIV-1 invistor-50 is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that targets HIV-1 reverse transcriptase (RT) (IC50=50 nM). HIV-1 inhibitor-50 shows significant antiviral activity, with EC50s of 2.22-53.3nM against HIV-1 IIIB and its mutant strains. | |||||||||||||||||||||
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Keywords
