2841750-53-4

Antitumor agent-100 hydrochloride Chemical Structure
2841750-53-4

Chemical Structure

Antitumor agent-100 hydrochloride

  • No. CAS: 2841750-53-4
  • Formula:C17H15Cl2N3O
  • Molecular Weight:348.23

InChIKey: LYJYIBIMUKOLLM-UHFFFAOYSA-N

SMILES: O=C1N=C2NC3=C(CN2C1)C(Cl)=C(C4=CC=C(C)C=C4)C=C3.Cl

Biological Activity: Antitumor agent-100 (compound A6) hydrochloride is an orally potent apoptosis inducer and molecular gel targeting PDE3A-SLFN12 (IC50: 0.3 μM) with antitumor activity. Antitumor agent-100 hydrochloride binds to the PDE3A enzyme pocket to recruit and stabilize SLFN12, thereby preventing protein translation and leading to apoptosis[1].

Referencia número Nombre del producto Pureza Descripciòn Pricing
HY-153802A 		Antitumor agent-100 hydrochloride Antitumor agent-100 (compound A6) hydrochloride is an orally potent apoptosis inducer and molecular gel targeting PDE3A-SLFN12 (IC50: 0.3 μM) with antitumor activity. Antitumor agent-100 hydrochloride binds to the PDE3A enzyme pocket to recruit and stabilize SLFN12, thereby preventing protein translation and leading to apoptosis.
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