2. Apoptosis Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE) Apoptosis
  4. Antitumor agent-100 hydrochloride

Antitumor agent-100 (compound A6) hydrochloride is an orally potent apoptosis inducer and molecular gel targeting PDE3A-SLFN12 (IC50: 0.3 μM) with antitumor activity. Antitumor agent-100 hydrochloride binds to the PDE3A enzyme pocket to recruit and stabilize SLFN12, thereby preventing protein translation and leading to apoptosis.

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Antitumor agent-100 hydrochloride Chemical Structure

Antitumor agent-100 hydrochloride Chemical Structure

CAS No. : 2841750-53-4

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Antitumor agent-100 hydrochloride Related Antibodies

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Description

Antitumor agent-100 (compound A6) hydrochloride is an orally potent apoptosis inducer and molecular gel targeting PDE3A-SLFN12 (IC50: 0.3 μM) with antitumor activity. Antitumor agent-100 hydrochloride binds to the PDE3A enzyme pocket to recruit and stabilize SLFN12, thereby preventing protein translation and leading to apoptosis[1].

IC50 & Target

IC50: 0.3 μM (PDE3A-SLFN12)[1]
Molecular Weight

348.23

Formula

C17H15Cl2N3O
CAS No.
SMILES

O=C1N=C2NC3=C(CN2C1)C(Cl)=C(C4=CC=C(C)C=C4)C=C3.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antitumor agent-100 hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitumor agent-1002841750-53-4 Antitumor agent100Antitumor agent 100Phosphodiesterase (PDE)ApoptosisInhibitorinhibitorinhibit

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