2873399-22-3
Chemical Structure
Tubulin polymerization-IN-2
- CAS No.: 2873399-22-3
- Formula:C17H12F2N2O2
- Molecular Weight:314.29
IUPAC Name: 2-amino-4-(3,4-difluorophenyl)-7-methoxy-4H-chromene-3-carbonitrile
InChIKey: HWVPIGBUNBADTM-UHFFFAOYSA-N
SMILES: COC1=CC2=C(C(C(C#N)=C(O2)N)C3=CC(F)=C(C=C3)F)C=C1
Biological Activity: Tubulin polymerization-IN-2 is a potent anticancer agent targeting to β-tubulin with an IC50 value of 0.92 μM. Tubulin polymerization-IN-2 shows promising activity against various leukemia, non-small lung, renal, prostate, and breast cancer cell lines[1].
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Tubulin polymerization-IN-2 | Tubulin polymerization-IN-2 is a potent anticancer agent targeting to β-tubulin with an IC50 value of 0.92 μM. Tubulin polymerization-IN-2 shows promising activity against various leukemia, non-small lung, renal, prostate, and breast cancer cell lines. | |||||||||||||||||||||
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Keywords