2879250-22-1
2879250-22-1
Chemical Structure
WIZ degrader 4
- CAS No.: 2879250-22-1
- Formula:C20H25N3O4
- Molecular Weight:371.43
InChIKey: VGRDATXDONRIRI-LDCVWXEPSA-N
SMILES: CCN1CCC[C@H](C1)OC2=CC=C3C(N(CC3=C2)C4CCC(NC4=O)=O)=O
Biological Activity: WIZ degrader 4 is a WIZ molecular glue degrader with an AC50 value of 16 nM. WIZ degrader 4 induces the expression of fetal hemoglobin (HbF) with an EC50 of 47 nM. WIZ degrader 4 can be used to investigate sickle cell disease (SCD) and thalassemia[1].
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WIZ degrader 4 | 99.37% | WIZ degrader 4 is a WIZ molecular glue degrader with an AC50 value of 16 nM. WIZ degrader 4 induces the expression of fetal hemoglobin (HbF) with an EC50 of 47 nM. WIZ degrader 4 can be used to investigate sickle cell disease (SCD) and thalassemia. | ||||||||||||||||||||
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