2883451-38-3
2883451-38-3
Chemical Structure
Carbonic anhydrase inhibitor 12
- CAS No.: 2883451-38-3
- Formula:C27H22BrN5O5S2
- Molecular Weight:640.53
IUPAC Name: 4-((2-((2-(4-bromophenyl)-2-oxoethyl)thio)-5-cyano-6-(2,5-dimethoxyphenyl)pyrimidin-4-yl)amino)benzenesulfonamide
InChIKey: AHXBLGYPELWYKD-UHFFFAOYSA-N
SMILES: COC1=CC=C(C(C2=NC(SCC(C3=CC=C(C=C3)Br)=O)=NC(NC4=CC=C(C=C4)S(N)(=O)=O)=C2C#N)=C1)OC
Biological Activity: Carbonic anhydrase inhibitor 12 is a potent CA II inhibitor, also has inhibitory activity in CA I (Kis of 1.72 and 271 nM in CA II and CA I, respectively). Carbonic anhydrase inhibitor 12 has potent anticancer activity against different cancer cell lines[1].
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Carbonic anhydrase inhibitor 12 | Carbonic anhydrase inhibitor 12 is a potent CA II inhibitor, also has inhibitory activity in CA I (Kis of 1.72 and 271 nM in CA II and CA I, respectively). Carbonic anhydrase inhibitor 12 has potent anticancer activity against different cancer cell lines. | |||||||||||||||||||||
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