2893801-00-6
Chemical Structure
D-685
- CAS No.: 2893801-00-6
- Formula:C32H39N3O3
- Molecular Weight:513.67
IUPAC Name: (S)-6-((2-(4-(4-(benzo[d][1,3]dioxol-5-yl)phenyl)piperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol
InChIKey: DZVFKWBBLHLLJQ-NDEPHWFRSA-N
SMILES: OC1=C2CC[C@H](N(CCN3CCN(C4=CC=C(C5=CC=C(OCO6)C6=C5)C=C4)CC3)CCC)CC2=CC=C1
Biological Activity: D-685, a prodrug of D-520, exhibits higher in vivo anti-Parkinsonian efficacy in a reserpinized Parkinson's disease (PD) animal model than the parent D-520. D-685 reduces accumulation of human α-synuclein (α-syn) protein. D-685 exhibits facile brain penetration[1].
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D-685 | D-685, a prodrug of D-520, exhibits higher in vivo anti-Parkinsonian efficacy in a reserpinized Parkinson's disease (PD) animal model than the parent D-520. D-685 reduces accumulation of human α-synuclein (α-syn) protein. D-685 exhibits facile brain penetration. | |||||||||||||||||||||
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Keywords