2987726-03-2
2987726-03-2
Chemical Structure
Topoisomerase inhibitor 6
- CAS No.: 2987726-03-2
- Formula:C20H22ClFN4O2
- Molecular Weight:404.87
SMILES: C[C@H](N)[C@H]1CN(C2=C(Cl)C(N(C3CC3)C(C4=C5OC(C)=N4)=O)=C5C=C2F)CC1
Biological Activity: Topoisomerase inhibitor 6 (Compound REDX05931) is a dual irreversible inhibitor of DNA gyrase and topoisomerase IV (MIC=0.06 μg/mL against fluoroquinolone-resistant S. aureus). Topoisomerase inhibitor 6 blocks DNA strand break-reunion, inducing lethal DNA damage. Topoisomerase inhibitor 6 is promising for research of Gram-positive bacterial infections (e.g., S. aureus, S. pneumoniae)[1].
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Topoisomerase inhibitor 6 | Topoisomerase inhibitor 6 (Compound REDX05931) is a dual irreversible inhibitor of DNA gyrase and topoisomerase IV (MIC=0.06 μg/mL against fluoroquinolone-resistant S. aureus). Topoisomerase inhibitor 6 blocks DNA strand break-reunion, inducing lethal DNA damage. Topoisomerase inhibitor 6 is promising for research of Gram-positive bacterial infections (e.g., S. aureus, S. pneumoniae). | |||||||||||||||||||||
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References
Keywords
