299420-83-0
Chemical Structure
UC-514321
- CAS No.: 299420-83-0
- Formula:C26H35NO5
- Molecular Weight:441.56
IUPAC Name: 6-((3,5-di-tert-butyl-4-hydroxyphenyl)(morpholino)methyl)benzo[d][1,3]dioxol-5-ol
InChIKey: XNARHFDDQALZPZ-UHFFFAOYSA-N
SMILES: OC1=C(C=C2OCOC2=C1)C(N3CCOCC3)C4=CC(C(C)(C)C)=C(C(C(C)(C)C)=C4)O
Biological Activity: UC-514321, a structural analog of NSC370284 with higher activity, directly targets STAT3/5 and represses TET1 expression, but not TET2 or TET3. UC-514321 has the potential to treat acute myeloid leukemia (AML) both in vitro and in vivo, with low toxicity[1].
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UC-514321 | 98.0% | UC-514321, a structural analog of NSC370284 with higher activity, directly targets STAT3/5 and represses TET1 expression, but not TET2 or TET3. UC-514321 has the potential to treat acute myeloid leukemia (AML) both in vitro and in vivo, with low toxicity. | ||||||||||||||||||||
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Keywords