3033395-24-0
Chemical Structure
Glutamate-5-kinase-IN-1
- CAS No.: 3033395-24-0
- Formula:C20H18N2O
- Molecular Weight:302.37
IUPAC Name: 4-(4-chlorophenyl)-7-fluoro-3H-pyrrolo[2,3-c]quinoline
InChIKey: XHZNSPQWRDWFGH-UHFFFAOYSA-N
SMILES: COC1=CC=C2C3=C(NC=C3)C(CCC4=CC=CC=C4)=NC2=C1
Biological Activity: Glutamate-5-kinase-IN-1 (compound 50) is a potent glutamate-5-kinase (G5K) inhibitor with an MIC (minimum inhibitory concentration) of 4.1 μM. Glutamate-5-kinase-IN-1 shows G5K inhibition by alters the ATP binding site architecture for enzyme recognition. Glutamate-5-kinase-IN-1 has the potential for the research of anti-TB agents[1].
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Glutamate-5-kinase-IN-1 | Glutamate-5-kinase-IN-1 (compound 50) is a potent glutamate-5-kinase (G5K) inhibitor with an MIC (minimum inhibitory concentration) of 4.1 μM. Glutamate-5-kinase-IN-1 shows G5K inhibition by alters the ATP binding site architecture for enzyme recognition. Glutamate-5-kinase-IN-1 has the potential for the research of anti-TB agents. | |||||||||||||||||||||
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Keywords
