3037850-79-3
3037850-79-3
Chemical Structure
ZC0109
- CAS No.: 3037850-79-3
- Formula:C22H20BrFN8O4S
- Molecular Weight:591.41
IUPAC Name: (Z)-2-(2,4-dihydroxybenzylidene)-7-hydroxybenzofuran-3(2H)-one
InChIKey: UEYJCFRMVBBVMR-UHFFFAOYSA-N
SMILES: O/N=C(C1=NON=C1NCCCC2=NN=C(S2)NC(CC3=CC=C(C=C3)O)=O)\NC4=CC(Br)=C(C=C4)F
Biological Activity: ZC0109 is a dual inhibitor of IDO1 and thioredoxin reductase 1 (TrxR1) with IC50s of 50 nM and 3.0 μM, respectively. ZC0109 induces ROS accumulation and cell cycle arrest at G1/S phase, thus leads to cancer cells apoptosis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ZC0109 | 99.86% | ZC0109 is a dual inhibitor of IDO1 and thioredoxin reductase 1 (TrxR1) with IC50s of 50 nM and 3.0 μM, respectively. ZC0109 induces ROS accumulation and cell cycle arrest at G1/S phase, thus leads to cancer cells apoptosis. | ||||||||||||||||||||
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References
Keywords
