3081803-13-3
3081803-13-3
Chemical Structure
HGPRT/TBrHGPRT1-IN-1
- No. CAS: 3081803-13-3
- Formula:C15H24N6O9P2
- Molecular Weight:494.33
InChIKey: APDUDHYPFAMPGN-ZJUUUORDSA-N
SMILES: NC1=NC2=C(C(N1)=O)N=CN2[C@@H]3C[C@H](N(C3)C(CCP(O)(O)=O)=O)COCCP(O)(O)=O
Biological Activity: HGPRT/TBrHGPRT1-IN-1 (Compound 5) is a selective inhibitor targeting human hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and Trypanosoma bruce HGPRT1 (TBrHGPRT1) (both Ki=3 nM). HGPRT/TBrHGPRT1-IN-1 ultimately results in decreased cell growth. HGPRT/TBrHGPRT1-IN-1 is primarily used in the research of infectious diseases and cancer[1].
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HGPRT/TBrHGPRT1-IN-1 | HGPRT/TBrHGPRT1-IN-1 (Compound 5) is a selective inhibitor targeting human hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and Trypanosoma bruce HGPRT1 (TBrHGPRT1) (both Ki=3 nM). HGPRT/TBrHGPRT1-IN-1 ultimately results in decreased cell growth. HGPRT/TBrHGPRT1-IN-1 is primarily used in the research of infectious diseases and cancer. | |||||||||||||||||||||
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