3092076-15-5
Chemical Structure
STAT6-IN-9
- CAS No.: 3092076-15-5
- Formula:C31H36N8O3
- Molecular Weight:568.67
InChIKey: DHPHSDTYOXZWGP-UHFFFAOYSA-N
SMILES: CN(C)C(C1=CN=C(C2=CC=C(N(N=C3C(NCC4=CC=C(NC(N5CCN(C)CC5)=O)C=C4)=O)CC)C3=C2)C=C1)=O
Biological Activity: STAT6-IN-9 is a potent STAT6 inhibitor with an EC50 value of 4 nM. STAT6-IN-9 effectively blocks STAT6 activation mediated by the IL-13-IL-13 receptor/IL-4 receptor pathway. STAT6-IN-9 inhibits CCL17 secretion with an IC50 value of 4.6 nM. STAT6-IN-9 can be used to investigate various chronic inflammatory diseases mediated by STAT6, such as allergy, asthma, and chronic obstructive pulmonary disease[1].
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STAT6-IN-9 | 98.11% | STAT6-IN-9 is a potent STAT6 inhibitor with an EC50 value of 4 nM. STAT6-IN-9 effectively blocks STAT6 activation mediated by the IL-13-IL-13 receptor/IL-4 receptor pathway. STAT6-IN-9 inhibits CCL17 secretion with an IC50 value of 4.6 nM. STAT6-IN-9 can be used to investigate various chronic inflammatory diseases mediated by STAT6, such as allergy, asthma, and chronic obstructive pulmonary disease. | ||||||||||||||||||||
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Keywords
