309913-42-6
309913-42-6
Chemical Structure
SX 011
- CAS No.: 309913-42-6
- Formula:C26H27ClFN3O3
- Molecular Weight:483.96
IUPAC Name: 2-(6-chloro-5-(4-(4-fluorobenzyl)piperidine-1-carbonyl)-1-methyl-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide
InChIKey: GUTYHDCSDBBMGW-UHFFFAOYSA-N
SMILES: O=C(N(C)C)C(C1=CN(C)C2=C1C=C(C(N3CCC(CC4=CC=C(F)C=C4)CC3)=O)C(Cl)=C2)=O
Biological Activity: SX 011 is a p38 inhibitor with IC50s of 9 nM and 90 nM against p38α and p38β, respectively. SX 011 also inhibits JNK-2 with an IC50 of 100 nM. SX-011 is orally bioavailable[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SX 011 | 99.33% | SX 011 is a p38 inhibitor with IC50s of 9 nM and 90 nM against p38α and p38β, respectively. SX 011 also inhibits JNK-2 with an IC50 of 100 nM. SX-011 is orally bioavailable. | ||||||||||||||||||||
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SX 011 (Standard) | ≥98% | SX 011 (Standard) is the analytical standard of SX 011 (HY-108646). This product is intended for research and analytical applications. SX 011 is a p38 inhibitor with IC50s of 9 nM and 90 nM against p38α and p38β, respectively. SX 011 also inhibits JNK-2 with an IC50 of 100 nM. SX-011 is orally bioavailable. | ||||||||||||||||||||
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References
Keywords
