SX 011 (Standard)
SX 011 (Standard) is the analytical standard of SX 011 (HY-108646). This product is intended for research and analytical applications. SX 011 is a p38 inhibitor with IC50s of 9 nM and 90 nM against p38α and p38β, respectively. SX 011 also inhibits JNK-2 with an IC50 of 100 nM. SX-011 is orally bioavailable.
For research use only. We do not sell to patients.
- CAS No.: 309913-42-6
- Formula: C26H27ClFN3O3
- Molecular Weight:483.96
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 309913-42-6
-
Molecular Weight 483.96
-
Formula C26H27ClFN3O3
-
SMILES
O=C(N(C)C)C(C1=CN(C)C2=C1C=C(C(N3CCC(CC4=CC=C(F)C=C4)CC3)=O)C(Cl)=C2)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Lee MR, et al. MAP kinase p38 inhibitors: clinical results and an intimate look at their interactions with p38alpha protein. Curr Med Chem. 2005;12(25):2979-94. [Content Brief]
[2]. Hynes J Jr, et al. Small molecule p38 inhibitors: novel structural features and advances from 2002-2005. Curr Top Med Chem. 2005;5(10):967-85. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)