2. Others MAPK/ERK Pathway
  3. Reference Standards p38 MAPK JNK
  4. SX 011 (Standard)

SX 011 (Standard) is the analytical standard of SX 011 (HY-108646). This product is intended for research and analytical applications. SX 011 is a p38 inhibitor with IC50s of 9 nM and 90 nM against p38α and p38β, respectively. SX 011 also inhibits JNK-2 with an IC50 of 100 nM. SX-011 is orally bioavailable.

For research use only. We do not sell to patients.

SX 011 (Standard)

SX 011 (Standard) Chemical Structure

CAS No. : 309913-42-6

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Information

SX 011 (Standard) is the analytical standard of SX 011 (HY-108646). This product is intended for research and analytical applications. SX 011 is a p38 inhibitor with IC50s of 9 nM and 90 nM against p38α and p38β, respectively. SX 011 also inhibits JNK-2 with an IC50 of 100 nM. SX-011 is orally bioavailable.

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight

483.96

Formula

C26H27ClFN3O3
CAS No.
SMILES

O=C(N(C)C)C(C1=CN(C)C2=C1C=C(C(N3CCC(CC4=CC=C(F)C=C4)CC3)=O)C(Cl)=C2)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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SX 011 (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SX 011 (Standard)309913-42-6Reference Standardsp38 MAPKJNKc-Jun N-terminal kinaseInhibitorinhibitorinhibit

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