3121287-19-9
Chemical Structure
PROTAC BCL6 Degrader-4
- CAS No.: 3121287-19-9
- Formula:C47H51ClF2N10O6
- Molecular Weight:925.42
InChIKey: GJNCRYAESQCMGP-OXYHUCQCSA-N
SMILES: CN1C(C2=C(C3=C1C=CC(NC4=NC(N5CCC(CC5)O[C@H]6C[C@@H](C6)N7CCC(CC7)C8=CC9=C(C(N(N=C9)C%10CCC(NC%10=O)=O)=O)C=C8)=NC=C4Cl)=C3)N[C@H](C(F)(CO2)F)C%11CC%11)=O
Biological Activity: PROTAC BCL6 Degrader-4 is a potent PROTAC BCL6 degrader. PROTAC BCL6 Degrader-4 recruits CRBN E3 ligase machinery to promote ubiquitination and proteasomal degradation of BCL6. PROTAC BCL6 Degrader-4 can be used for the research of diffuse large B-cell lymphoma and related hematological malignancies[1].
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PROTAC BCL6 Degrader-4 | PROTAC BCL6 Degrader-4 is a potent PROTAC BCL6 degrader. PROTAC BCL6 Degrader-4 recruits CRBN E3 ligase machinery to promote ubiquitination and proteasomal degradation of BCL6. PROTAC BCL6 Degrader-4 can be used for the research of diffuse large B-cell lymphoma and related hematological malignancies. | |||||||||||||||||||||
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Keywords
