332950-12-6
332950-12-6
Chemical Structure
ISR activator 3
- CAS No.: 332950-12-6
- Formula:C23H21N3O3S2
- Molecular Weight:451.56
InChIKey: BPVWCTZLAKMQDH-UHFFFAOYSA-N
SMILES: CC1=C2C(SC(C(NC3=C(C(OCC)=O)C(C4=CC=CC=C4)=CS3)=O)=C2N)=NC(C)=C1
Biological Activity: ISR activator 3 (Compound cc81) is the active metabolite of A8. ISR activator 3 activates the integrated stress response (ISR) by binding to RIG-I (KD ≈ 0.55 μM), without inducing lipid droplet clearance. ISR activator 3 enhances the interferon response under viral mimicry signals. ISR activator 3 can be used for research on neurodegenerative diseases and immune stress[1].
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ISR activator 3 | ISR activator 3 (Compound cc81) is the active metabolite of A8. ISR activator 3 activates the integrated stress response (ISR) by binding to RIG-I (KD ≈ 0.55 μM), without inducing lipid droplet clearance. ISR activator 3 enhances the interferon response under viral mimicry signals. ISR activator 3 can be used for research on neurodegenerative diseases and immune stress. | |||||||||||||||||||||
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