344900-92-1
344900-92-1
Chemical Structure
FTI-2153
- CAS No.: 344900-92-1
- Formula:C25H30N4O3S
- Molecular Weight:466.60
IUPAC Name: methyl (5-((((1H-imidazol-5-yl)methyl)amino)methyl)-2'-methyl-[1,1'-biphenyl]-2-carbonyl)-L-methioninate
InChIKey: KZCMMZOLCBZLNG-QHCPKHFHSA-N
SMILES: CSCC[C@@H](C(OC)=O)NC(C1=CC=C(CNCC2=CN=CN2)C=C1C3=CC=CC=C3C)=O
Biological Activity: FTI-2153 is a potent and highly selective inhibitor of farnesyltransferase (FTase), with an IC50 of 1.4 nM. FTI-2153 is >3000-fold more potent at blocking H-Ras (IC50, 10 nM) than Rap1A processing. Anti-cancer activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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FTI-2153 | 99.77% | FTI-2153 is a potent and highly selective inhibitor of farnesyltransferase (FTase), with an IC50 of 1.4 nM. FTI-2153 is >3000-fold more potent at blocking H-Ras (IC50, 10 nM) than Rap1A processing. Anti-cancer activity. | ||||||||||||||||||||
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References
Keywords
