359595-95-2
359595-95-2
Chemical Structure
MDM2/XIAP-IN-1
- CAS No.: 359595-95-2
- Formula:C28H28N2O4S
- Molecular Weight:488.60
IUPAC Name: methyl 4-(8-(N-(3,4-dimethylphenyl)sulfamoyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)benzoate
InChIKey: HLWMVSWXILODEG-UHFFFAOYSA-N
SMILES: O=C(OC)C1=CC=C(C2NC3=C(C=C(S(=O)(NC4=CC=C(C)C(C)=C4)=O)C=C3)C5C2CC=C5)C=C1
Biological Activity: MDM2/XIAP-IN-1 (compound 14) is an orally active inhibitor of dual MDM2/XIAP. MDM2/XIAP-IN-1 has anti-cancer activity with an IC50 value of 0.3 μM, which can be used in cance rescrch[1].
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MDM2/XIAP-IN-1 | MDM2/XIAP-IN-1 (compound 14) is an orally active inhibitor of dual MDM2/XIAP. MDM2/XIAP-IN-1 has anti-cancer activity with an IC50 value of 0.3 μM, which can be used in cance rescrch. | |||||||||||||||||||||
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