3627-51-8
Chemical Structure
Monascorubramine
- CAS No.: 3627-51-8
- Formula:C23H27NO4
- Molecular Weight:381.46
IUPAC Name: (2S,3R,4S,5S,6R)-4,5-dihydroxy-2-(2-((((S)-1-hydroxy-6-oxocyclohex-2-ene-1-carbonyl)oxy)methyl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl benzoate
InChIKey: QCUYNKMUDZHGNK-HAOIVFDCSA-N
SMILES: C/C=C/C(NC=C1C2=O)=CC1=CC([C@]23C)=C(C(O3)=O)C(CCCCCCC)=O
Biological Activity: Monascorubramine is a metabolite derived from Monascus with antibacterial, cytotoxic and antimitotic activities. Monascorubramine interferes with mitotic spindle tubulin, triggers metaphase mitotic arrest, induces abnormal c‑mitosis division, and exerts antimitotic effects. Monascorubramine exhibits antibacterial activity and inhibits both Gram-positive and Gram-negative bacteria. Monascorubramine can be used in studies related to bacterial infections[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Monascorubramine | 99.15% | Monascorubramine is a metabolite derived from Monascus with antibacterial, cytotoxic and antimitotic activities. Monascorubramine interferes with mitotic spindle tubulin, triggers metaphase mitotic arrest, induces abnormal c‑mitosis division, and exerts antimitotic effects. Monascorubramine exhibits antibacterial activity and inhibits both Gram-positive and Gram-negative bacteria. Monascorubramine can be used in studies related to bacterial infections. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Knecht A, et al. Cytotoxic and antimitotic effects of N-containing Monascus metabolites studied using immortalized human kidney epithelial cells. Molecular nutrition & food research. 2006 Apr;50(4-5):406-12.
- [2]. Albisoru D, et al. Studies Regarding Antimicrobial Properties of Some Microbial Polyketides Derived from Strains. Antibiotics (Basel, Switzerland). 2024 Nov 16;13(11):1092.
Keywords
