506429-34-1
Chemical Structure
YycG-IN-1
- CAS No.: 506429-34-1
- Formula:C30H33N3O5S
- Molecular Weight:547.67
IUPAC Name: ethyl 2-((4-methylpiperazin-1-yl)methyl)-1-phenyl-5-(tosyloxy)-1H-indole-3-carboxylate
InChIKey: ASVHIXQPSDYYMK-UHFFFAOYSA-N
SMILES: O=C(OCC)C=1C=2C=C(OS(=O)(=O)C3=CC=C(C=C3)C)C=CC2N(C=4C=CC=CC4)C1CN5CCN(C)CC5
Biological Activity: YycG-IN-1 is a selective YycG inhibitor, with an IC50 of 42.9 μM and a Kd of 86.4 μM against YycG from Enterococcus faecalis. YycG-IN-1 inhibits the kinase activity and autophosphorylation activity of YycG, suppresses biofilm formation of Enterococcus faecalis, inhibits the planktonic growth of Enterococcus faecalis, and exerts effects on multiple mutant strains of Enterococcus faecalis. YycG-IN-1 can be used in studies related to Enterococcus faecalis infection[1].
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YycG-IN-1 | YycG-IN-1 is a selective YycG inhibitor, with an IC50 of 42.9 μM and a Kd of 86.4 μM against YycG from Enterococcus faecalis. YycG-IN-1 inhibits the kinase activity and autophosphorylation activity of YycG, suppresses biofilm formation of Enterococcus faecalis, inhibits the planktonic growth of Enterococcus faecalis, and exerts effects on multiple mutant strains of Enterococcus faecalis. YycG-IN-1 can be used in studies related to Enterococcus faecalis infection. | |||||||||||||||||||||
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