51803-78-2
51803-78-2
Chemical Structure
Nimesulide
Synonym(s): R805
- CAS No.: 51803-78-2
- Formula:C13H12N2O5S
- Molecular Weight:308.31
IUPAC Name: N-(4-nitro-2-phenoxyphenyl)methanesulfonamide
InChIKey: HYWYRSMBCFDLJT-UHFFFAOYSA-N
SMILES: CS(=O)(NC1=CC=C([N+]([O-])=O)C=C1OC2=CC=CC=C2)=O
Biological Activity: Nimesulide is a selective COX-2 inhibitor, with IC50s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties.
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Nimesulide | 99.89% | Nimesulide is a selective COX-2 inhibitor, with IC50s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties. | ||||||||||||||||||||
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Nimesulide (Standard) | ≥98% | Nimesulide (Standard) is the analytical standard of Nimesulide. This product is intended for research and analytical applications. Nimesulide is a selective COX-2 inhibitor, with IC50s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties. | ||||||||||||||||||||
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Nimesulide-13C6 | Nimesulide-13C6 (R805-13C6) is 13C labeled Nimesulide. Nimesulide is a selective COX-2 inhibitor, with IC50s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties. | |||||||||||||||||||||
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Nimesulide-d5 | 99.9% | Nimesulide-d5 is a deuterium labeled Nimesulide. Nimesulide is a selective COX-2 inhibitor, with IC50s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties. | ||||||||||||||||||||
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