518044-40-1
Chemical Structure
Maleimido-tri(ethylene glycol)-propionic acid
Synonym(s): Mal-PEG3-acid
- CAS No.: 518044-40-1
- Formula:C13H19NO7
- Molecular Weight:301.29
IUPAC Name: 3-(2-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)ethoxy)propanoic acid
InChIKey: YSFOTVPQFVYTQX-UHFFFAOYSA-N
SMILES: O=C(O)CCOCCOCCOCCN1C(C=CC1=O)=O
Biological Activity: Maleimido-tri(ethylene glycol)-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Maleimido-tri(ethylene glycol)-propionic acid is used for the preparation of neolymphostin-based ADC precursors for site-specific cysteine mutant trastuzumab-A114C conjugation[1]. Maleimido-tri(ethylene glycol)-propionic acid also can be used as a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Maleimido-tri(ethylene glycol)-propionic acid | 98.0% | Maleimido-tri(ethylene glycol)-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Maleimido-tri(ethylene glycol)-propionic acid is used for the preparation of neolymphostin-based ADC precursors for site-specific cysteine mutant trastuzumab-A114C conjugation. Maleimido-tri(ethylene glycol)-propionic acid also can be used as a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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