59733-86-7
59733-86-7
Chemical Structure
Butikacin
Synonym(s): UK-18892
- CAS. Nr.: 59733-86-7
- Formula:C22H45N5O12
- Molecular Weight:571.62
InChIKey: OCFOTEIMZBKQFS-DGMGPCKZSA-N
SMILES: NCC[C@H](O)CN[C@H]1[C@H](O[C@@H]2[C@H](O)[C@@H](N)[C@H](O)[C@@H](CO)O2)[C@@H](O)[C@H](O[C@@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CN)O3)[C@@H](N)C1
Biological Activity: Butikacin (UK-18892) is an antibiotic and a derivative of Kanamycin (HY-16566). Butikacin resists most aminoglycoside-inactivating enzymes through its structure, thereby inhibiting bacterial growth. Butikacin can be used in research on bacterial infections[1][2][3].
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Butikacin | Butikacin (UK-18892) is an antibiotic and a derivative of Kanamycin (HY-16566). Butikacin resists most aminoglycoside-inactivating enzymes through its structure, thereby inhibiting bacterial growth. Butikacin can be used in research on bacterial infections. | |||||||||||||||||||||
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References
- [1]. Carter AJ, et al. Cochlear toxicity of butikacin (UK-18,892), a new semisynthetic aminoglycoside antibiotic, in guinea pigs. Antimicrobial agents and chemotherapy. 1979 Sep;16(3):362-5.
- [2]. Wise R, et al. UK-18892, a new aminoglycoside: an in vitro study. Antimicrob Agents Chemother. 1978 Aug;14(2):228-33.
- [3]. TROLLFORS B, et al. Effect on the renal function of UK 18892. Journal of Antimicrobial Chemotherapy, 1980, 6(5): 685-687.
