65318-21-0
Chemical Structure
Mycosporine glycine
Synonym(s): Mycosporine-Gly
- CAS No.: 65318-21-0
- Formula:C10H15NO6
- Molecular Weight:245.23
InChIKey: XZQILKYKJYHEHD-JTQLQIEISA-N
SMILES: OC(CNC1=C(C(C[C@@](O)(C1)CO)=O)OC)=O
Biological Activity: Mycosporine glycine (Mycosporine-Gly) is a mycosporine-like amino acid derived from marine organisms, which possesses free radical scavenging, antioxidant, anti-inflammatory and photoprotective activities. Mycosporine glycine inhibits the UV-induced upregulation of COX-2 mRNA and gene expression levels, scavenges free radicals, ROS and peroxyl radicals, and inhibits free radical chain lipid peroxidation and phosphatidylcholine peroxidation. Mycosporine glycine restores PCOLCE and elastin levels suppressed by ultraviolet radiation, alleviates photooxidative stress and UV-mediated skin cell damage. Mycosporine glycine can be used in studies related to UV-induced skin inflammation, skin photoaging and skin damage[1][2][3].
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Mycosporine glycine | Mycosporine glycine (Mycosporine-Gly) is a mycosporine-like amino acid derived from marine organisms, which possesses free radical scavenging, antioxidant, anti-inflammatory and photoprotective activities. Mycosporine glycine inhibits the UV-induced upregulation of COX-2 mRNA and gene expression levels, scavenges free radicals, ROS and peroxyl radicals, and inhibits free radical chain lipid peroxidation and phosphatidylcholine peroxidation. Mycosporine glycine restores PCOLCE and elastin levels suppressed by ultraviolet radiation, alleviates photooxidative stress and UV-mediated skin cell damage. Mycosporine glycine can be used in studies related to UV-induced skin inflammation, skin photoaging and skin damage. | |||||||||||||||||||||
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- [1]. Suh SS, et al. Anti-inflammation activities of mycosporine-like amino acids (MAAs) in response to UV radiation suggest potential anti-skin aging activity. Marine drugs. 2014 Oct 14;12(10):5174-87.
- [2]. Singh A, et al. Exploring Mycosporine-Like Amino Acids (MAAs) as Safe and Natural Protective Agents against UV-Induced Skin Damage. Antioxidants (Basel, Switzerland). 2021 Apr 27;10(5):683.
- [3]. Dunlap W C. Small‑molecule antioxidants in marine organisms: Antioxidant activity of mycosporine‑glycine. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 1995, 112(1): 105‑114.
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