67884-10-0
Chemical Structure
Glucocamelinin
Synonym(s): 10-(Methylsulfinyl)decylglucosinolate; GSL 10
- CAS No.: 67884-10-0
- Formula:C18H35NO10S3
- Molecular Weight:521.67
InChIKey: PPIATLIUZMGEJB-IFKGCRCZSA-N
SMILES: CS(CCCCCCCCCC/C(S[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)=N/OS(=O)(O)=O)=O
Biological Activity: Glucocamelinin (GSL 10) is a sulfinyl glucosinolate identified from seeds of Camelina sativa and an upregulator of quinone reductase (NQO1). Glucocamelinin upregulates the activity of phase II detoxifying enzymes, exhibits selective cytotoxic activity against lung cancer cells, and possesses in vitro antioxidant activity. Glucocamelinin can be used in studies related to non-small cell lung cancer[1][2][3][4][5].
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Glucocamelinin | Glucocamelinin (GSL 10) is a sulfinyl glucosinolate identified from seeds of Camelina sativa and an upregulator of quinone reductase (NQO1). Glucocamelinin upregulates the activity of phase II detoxifying enzymes, exhibits selective cytotoxic activity against lung cancer cells, and possesses in vitro antioxidant activity. Glucocamelinin can be used in studies related to non-small cell lung cancer. | |||||||||||||||||||||
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- [1]. Das N, et al. Camelina sativa defatted seed meal contains both alkyl sulfinyl glucosinolates and quercetin that synergize bioactivity. Journal of agricultural and food chemistry. 2014 Aug 20;62(33):8385-91. [Content Brief]
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[2]. Mark A, et al. Optimized analysis and quantification of glucosinolates from Camelina sativa seeds by reverse-phase liquid chromatography, Industrial Crops and Products, Volume 43, 2013, Pages 119-125, ISSN 0926-6690.
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[3]. Čeh, et al. Glucosinulates content in camelina (Camelina sativa (L.) Crantz) seeds and oilcakes with regard to production location. Hop Bulletin. 2013. 20. 82-89.
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[4]. A Schuster, et al. Glucosinolate content and composition as parameters of quality of Camelina seed, Industrial Crops and Products, Volume 7, Issues 2-3, 1998, Pages 297-302, ISSN 0926-6690.
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[5]. Elena Ponzoni, et al. Comparative effects of glucosinolate-derived isothiocyanates from Camelina sativa seeds and sulforaphane on A549 lung cancer cells, Journal of Agriculture and Food Research, Volume 21, 2025, 101982, ISSN 2666-1543.
Keywords
