6964-20-1
Chemical Structure
Tiadenol
- CAS No.: 6964-20-1
- Formula:C14H30O2S2
- Molecular Weight:294.52
IUPAC Name: 2,2'-(decane-1,10-diylbis(sulfanediyl))bis(ethan-1-ol)
InChIKey: WRCITXQNXAIKLR-UHFFFAOYSA-N
SMILES: OCCSCCCCCCCCCCSCCO
Biological Activity: Tiadenol is an absorbable hypolipidemic agent. Tiadenol can effectively reduce triglycerides and decrease the level of apolipoprotein E in very low-density lipoproteins in hyperlipoproteinemia. Tiadenol causes hepatomegaly in rats and affects their hepatic lipid levels, cholesterol synthesis and absorption at high doses. Tiadenol can be used in the research of endocrine and metabolic diseases such as hyperlipidemia[1][2].
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Tiadenol | Tiadenol is an absorbable hypolipidemic agent. Tiadenol can effectively reduce triglycerides and decrease the level of apolipoprotein E in very low-density lipoproteins in hyperlipoproteinemia. Tiadenol causes hepatomegaly in rats and affects their hepatic lipid levels, cholesterol synthesis and absorption at high doses. Tiadenol can be used in the research of endocrine and metabolic diseases such as hyperlipidemia. | |||||||||||||||||||||
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- [1]. Kritchevsky D, et al. Influence of tiadenol, bis-(hydroxyethylthio)1,10-decane, on cholesterol metabolism in rats. Pharmacol Res Commun. 1979 Nov;11(10):861-7. [Content Brief]
- [2]. Franceschini G, et al. Pharmacological studies on tiadenol in type IV patients. Evidence for a mechanism of action different from other lipid-lowering drugs. Atherosclerosis. 1981 Nov-Dec;40(3-4):245-55. [Content Brief]
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