708218-62-6
708218-62-6
Chemical Structure
B-Raf IN 19
- CAS No.: 708218-62-6
- Formula:C20H15NO3S3
- Molecular Weight:413.53
InChIKey: ANWROCYWIBTMKJ-UHFFFAOYSA-N
SMILES: O=S(NC1=CC(SC2=CC=CC=C2)=C(C3=C1C=CC=C3)O)(C4=CC=CS4)=O
Biological Activity: B-Raf IN 19 (compound 31) is a BRAF inhibitor that inhibits BRAF(WT) and BRAF(V600E) (IC50: 0.57 μM and 0.28 μM, respectively). B-Raf IN 19 inhibits MAPK signaling in melanoma cells[1].
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B-Raf IN 19 | B-Raf IN 19 (compound 31) is a BRAF inhibitor that inhibits BRAF(WT) and BRAF(V600E) (IC50: 0.57 μM and 0.28 μM, respectively). B-Raf IN 19 inhibits MAPK signaling in melanoma cells. | |||||||||||||||||||||
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References
Keywords
