72853-81-7
Chemical Structure
(+)-Aureol
- CAS No.: 72853-81-7
- Formula:C21H30O2
- Molecular Weight:314.46
InChIKey: UYLGYRGJFUJKFM-PXNLJIHASA-N
SMILES: C[C@]12[C@@]3(OC4=CC=C(O)C=C4C2)[C@](CC[C@@H]1C)([H])C(C)(CCC3)C
Biological Activity: (+)-Aureol is a tetracyclic benzopyran-fused decalin-type 9-norspongiane heteroterpenoid. (+)-Aureol exhibits antifungal activity, with an EC50 value of 6.9 μM against Rhizoctonia solani and an EC50 value of 19 μM against Sclerotinia sclerotiorum. (+)-Aureol shows selective inhibitory activity against human tumor cells. (+)-Aureol acts as an anti-influenza agent with activity against influenza A virus. (+)-Aureol can be used in research related to fungal infections, non-small cell lung cancer, colon adenocarcinoma and influenza A virus infections[1][2].
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(+)-Aureol | (+)-Aureol is a tetracyclic benzopyran-fused decalin-type 9-norspongiane heteroterpenoid. (+)-Aureol exhibits antifungal activity, with an EC50 value of 6.9 μM against Rhizoctonia solani and an EC50 value of 19 μM against Sclerotinia sclerotiorum. (+)-Aureol shows selective inhibitory activity against human tumor cells. (+)-Aureol acts as an anti-influenza agent with activity against influenza A virus. (+)-Aureol can be used in research related to fungal infections, non-small cell lung cancer, colon adenocarcinoma and influenza A virus infections. | |||||||||||||||||||||
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- [1]. Sun S, et al.. Facile Synthesis and First Antifungal Exploration of Tetracyclic Meroterpenoids: (+)-Aureol, (-)-Pelorol, and Its Analogs. Journal of natural products. 2024 Apr 26;87(4):1092-1102. [Content Brief]
- [2]. Kuan KK, et al.. Total synthesis of (+)-aureol. Organic letters. 2012 Sep 21;14(18):4710-3. [Content Brief]
Keywords
