2. Anti-infection
  3. Fungal Influenza Virus
  4. (+)-Aureol

(+)-Aureol is a tetracyclic benzopyran-fused decalin-type 9-norspongiane heteroterpenoid. (+)-Aureol exhibits antifungal activity, with an EC50 value of 6.9 μM against Rhizoctonia solani and an EC50 value of 19 μM against Sclerotinia sclerotiorum. (+)-Aureol shows selective inhibitory activity against human tumor cells. (+)-Aureol acts as an anti-influenza agent with activity against influenza A virus. (+)-Aureol can be used in research related to fungal infections, non-small cell lung cancer, colon adenocarcinoma and influenza A virus infections.

For research use only. We do not sell to patients.

(+)-Aureol

(+)-Aureol Chemical Structure

CAS No. : 72853-81-7

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(+)-Aureol Related Antibodies

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Description

(+)-Aureol is a tetracyclic benzopyran-fused decalin-type 9-norspongiane heteroterpenoid. (+)-Aureol exhibits antifungal activity, with an EC50 value of 6.9 μM against Rhizoctonia solani and an EC50 value of 19 μM against Sclerotinia sclerotiorum. (+)-Aureol shows selective inhibitory activity against human tumor cells. (+)-Aureol acts as an anti-influenza agent with activity against influenza A virus. (+)-Aureol can be used in research related to fungal infections, non-small cell lung cancer, colon adenocarcinoma and influenza A virus infections[1][2].

In Vitro

(+)-Aureol (compound 22) (0.78125-50 μg/mL; fungal growth period) potently inhibits the growth of Rhizoctonia solani with an EC50 of 6.9 μM[1].
(+)-Aureol (0.78125-50 μg/mL; fungal growth period) inhibits the growth of Sclerotinia sclerotiorum with an EC50 of 19 μM[1].
(+)-Aureol (150 μM; fungal growth period) inhibits the growth of Botrytis cinerea (62%), Fusarium graminearum (66%), and Phytophthora capsica (57%)[1].
(+)-Aureol (compound 1) exhibits selective cytotoxicity against human nonsmall cell lung cancer A549 cells and human colon adenocarcinoma HT-29 cells[2].
(+)-Aureol possesses potent activity against influenza A virus[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(+)-Aureol Related Antibodies
Molecular Weight

314.46

Formula

C21H30O2
CAS No.
SMILES

C[C@]12[C@@]3(OC4=CC=C(O)C=C4C2)[C@](CC[C@@H]1C)([H])C(C)(CCC3)C
Structure Classification
Initial Source

Smenospongia aurea
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(+)-Aureol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(+)-Aureol72853-81-7FungalInfluenza VirusRhizoctonia solaniVerongula giganteaSmenospongia aureaFusarium graminearumnonsmall cell lung cancerSclerotinia sclerotiorumPhytophthora capsicainfluenza A virusBotrytis cinereacolon adenocarcinomaInhibitorinhibitorinhibit

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