815595-25-6
815595-25-6
Chemical Structure
p38 Kinase inhibitor 8
- CAS No.: 815595-25-6
- Formula:C22H21FN6O2
- Molecular Weight:420.44
InChIKey: LRESELHEXSUQGE-UHFFFAOYSA-N
SMILES: O=C(C)N1CCC(CC1)NC2=NC(C3=C(C4=CC=C(C=C4)F)N=C5OC=CN53)=CC=N2
Biological Activity: p38 Kinase inhibitor 8 (Compound CCLXXVIII) is the orally active inhibitor for p38β and JNK2α2 with IC50s of 6.3 nM and 53.6 nM. p38 Kinase inhibitor 8 exhibits anti-inflammatory effect in rats collagen-induced arthritis models[1].
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p38 Kinase inhibitor 8 | p38 Kinase inhibitor 8 (Compound CCLXXVIII) is the orally active inhibitor for p38β and JNK2α2 with IC50s of 6.3 nM and 53.6 nM. p38 Kinase inhibitor 8 exhibits anti-inflammatory effect in rats collagen-induced arthritis models. | |||||||||||||||||||||
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