p38 Kinase inhibitor 8
p38 Kinase inhibitor 8 (Compound CCLXXVIII) is the orally active inhibitor for p38β and JNK2α2 with IC50s of 6.3 nM and 53.6 nM. p38 Kinase inhibitor 8 exhibits anti-inflammatory effect in rats collagen-induced arthritis models.
For research use only. We do not sell to patients.
- CAS No.: 815595-25-6
- Formula: C22H21FN6O2
- Molecular Weight:420.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 815595-25-6
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Molecular Weight 420.44
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Formula C22H21FN6O2
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SMILES
O=C(C)N1CCC(CC1)NC2=NC(C3=C(C4=CC=C(C=C4)F)N=C5OC=CN53)=CC=N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)