82117-51-9
Chemical Structure
Cinuperone
- CAS No.: 82117-51-9
- Formula:C23H24FN3O
- Molecular Weight:377.46
IUPAC Name: 1-(4-fluorophenyl)-4-(4-(isoquinolin-3-yl)piperazin-1-yl)butan-1-one
InChIKey: YLCFZLMWTUMGKY-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(F)C=C1)CCCN2CCN(C=3N=CC4=CC=CC=C4C3)CC2
Biological Activity: Cinuperone is a multi-target competitive receptor ligand and σ receptor antagonist that acts on Dopamine D1, σ, Dopamine D1, and 5-HT2 receptors. Cinuperone shows significantly higher affinity for σ receptors than for Dopamine D1 receptors, and only exhibits moderate binding activity for dopamine D2 receptors. Cinuperone can be used in the research of central nervous system diseases[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Cinuperone | Cinuperone is a multi-target competitive receptor ligand and σ receptor antagonist that acts on Dopamine D1, σ, Dopamine D1, and 5-HT2 receptors. Cinuperone shows significantly higher affinity for σ receptors than for Dopamine D1 receptors, and only exhibits moderate binding activity for dopamine D2 receptors. Cinuperone can be used in the research of central nervous system diseases. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Berardi F, et al. New σ and 5-HT₁A Receptor Ligands: ω-(Tetralin-1-yl)-n-alkylamine Derivatives. Journal of Medicinal Chemistry. 1996;39(1):176-182.
- [2]. Lang A, et al. Pharmacological comparison of antipsychotic drugs and sigma-antagonists in rodents. Pharmacology & toxicology. 1994;75(3-4):222-7. [Content Brief]
Keywords
