839707-37-8
Chemical Structure
Pluripotin
Synonym(s): SC1
- CAS No.: 839707-37-8
- Formula:C27H25F3N8O2
- Molecular Weight:550.54
IUPAC Name: N-(3-(7-((1,3-dimethyl-1H-pyrazol-5-yl)amino)-1-methyl-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
InChIKey: NBZFRTJWEIHFPF-UHFFFAOYSA-N
SMILES: CN1C(NC2=NC=C3C(N(C)C(N(C4=CC(NC(C5=CC=CC(C(F)(F)F)=C5)=O)=CC=C4C)C3)=O)=N2)=CC(C)=N1
Biological Activity: Pluripotin is a dual inhibitor of ERK1 and RasGAP with KDs of 98 nM and 212 nM, respectively. Pluripotin also inhibits RSK1, RSK2, RSK3, and RSK4 with IC50s of 0.5, 2.5, 3.3, and 10.0 μM, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pluripotin | 98.86% | Pluripotin is a dual inhibitor of ERK1 and RasGAP with KDs of 98 nM and 212 nM, respectively. Pluripotin also inhibits RSK1, RSK2, RSK3, and RSK4 with IC50s of 0.5, 2.5, 3.3, and 10.0 μM, respectively. | ||||||||||||||||||||
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Pluripotin (Standard) | ≥98% | Pluripotin (Standard) is the analytical standard of Pluripotin (HY-10579). This product is intended for research and analytical applications. Pluripotin is a dual inhibitor of ERK1 and RasGAP with KDs of 98 nM and 212 nM, respectively. Pluripotin also inhibits RSK1, RSK2, RSK3, and RSK4 with IC50s of 0.5, 2.5, 3.3, and 10.0 μM, respectively. | ||||||||||||||||||||
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Keywords
