85073-19-4
Chemical Structure
LAP
Synonym(s): Lithium phenyl-2,4,6-trimethylbenzoylphosphinate
- CAS No.: 85073-19-4
- Formula:C16H16LiO3P
- Molecular Weight:294.22
IUPAC Name: lithium phenyl(2,4,6-trimethylbenzoyl)phosphinate
InChIKey: JUYQFRXNMVWASF-UHFFFAOYSA-M
SMILES: O=P(C(C1=C(C)C=C(C)C=C1C)=O)(C2=CC=CC=C2)O[Li]
Biological Activity: LAP (Lithium phenyl-2,4,6-trimethylbenzoylphosphinate) is a free radical initiator. The free radicals produced by LAP under bioprinting conditions are potentially cytotoxic and mutagenic. In addition, the concentration of LAP affects the mechanical strength of 3D printed scaffolds. Generally, the concentration range of LAP used for curing is 0.05%-1%. The elastic modulus produced at a concentration of 0.1% is the highest, with enhanced mechanical properties and excellent biocompatibility[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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LAP | 99.84% | LAP (Lithium phenyl-2,4,6-trimethylbenzoylphosphinate) is a free radical initiator. The free radicals produced by LAP under bioprinting conditions are potentially cytotoxic and mutagenic. In addition, the concentration of LAP affects the mechanical strength of 3D printed scaffolds. Generally, the concentration range of LAP used for curing is 0.05%-1%. The elastic modulus produced at a concentration of 0.1% is the highest, with enhanced mechanical properties and excellent biocompatibility. | ||||||||||||||||||||
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- [1]. Nguyen AK, et al. The Photoinitiator Lithium Phenyl (2,4,6-Trimethylbenzoyl) Phosphinate with Exposure to 405 nm Light Is Cytotoxic to Mammalian Cells but Not Mutagenic in Bacterial Reverse Mutation Assays. Polymers (Basel). 2020 Jul 3;12(7):1489. [Content Brief]
- [2]. Qian Feng, et al. "Multi-modal imaging for dynamic visualization of osteogenesis and implant degradation in 3D bioprinted scaffolds." Bioactive Materials 37 (2024): 119-131. [Content Brief]
- [3]. Nguyen, et al. Toxicity and photosensitizing assessment of gelatin methacryloyl-based hydrogels photoinitiated with lithium phenyl-2, 4, 6-trimethylbenzoylphosphinate in human primary renal proximal tubule epithelial cells. Biointerphases 14.2 (2019). [Content Brief]
Keywords