887781-62-6
887781-62-6
Chemical Structure
MK-0674
- CAS No.: 887781-62-6
- Formula:C26H27F6N3O2
- Molecular Weight:527.50
IUPAC Name: (S)-N-(1-cyanocyclopropyl)-2-(((S)-1-(4'-((R)-2,2-difluoro-1-hydroxyethyl)-[1,1'-biphenyl]-4-yl)-2,2,2-trifluoroethyl)amino)-4-fluoro-4-methylpentanamide
InChIKey: YTEORGORWDMMRK-HBMCJLEFSA-N
SMILES: FC(F)(F)[C@H](C1=CC=C(C2=CC=C(C=C2)[C@@H](O)C(F)F)C=C1)N[C@@H](CC(C)(F)C)C(NC3(CC3)C#N)=O
Biological Activity: MK-0674 is a potent, orally bioavailable and selective cathepsin K inhibitor, with an IC50 of 0.4 nM, shows 1156, 1465, 11857 and 243 fold selectivity over Cat B, Cat F, Cat L and Cat S[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
MK-0674 | MK-0674 is a potent, orally bioavailable and selective cathepsin K inhibitor, with an IC50 of 0.4 nM, shows 1156, 1465, 11857 and 243 fold selectivity over Cat B, Cat F, Cat L and Cat S. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
