898532-85-9
Chemical Structure
D3/5-HT receptor modulator-1
- CAS No.: 898532-85-9
- Formula:C24H29N3O2
- Molecular Weight:391.51
IUPAC Name: N-(4-(4-(m-tolyl)piperazin-1-yl)butyl)benzofuran-2-carboxamide
InChIKey: DIJKUIXRAWOVGJ-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=CC=CC=C2O1)NCCCCN3CCN(C4=CC=CC(C)=C4)CC3
Biological Activity: D3/5-HT receptor modulator-1 (compound 5i) is a selective dopamine D3 receptor and 5-HT2A receptor antagonist and a partial 5-HT1A receptor agonist. D3/5-HT receptor modulator-1 shows Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for dopamine D3, 5-HT2A, and 5-HT2A receptors. D3/5-HT receptor modulator-1 has a low affinity for dopamine D2 receptors, 5-HT2C receptors, and hERG channels. D3/5-HT receptor modulator-1 has an atypical antipsychotic profile[1].
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D3/5-HT receptor modulator-1 | 99.75% | D3/5-HT receptor modulator-1 (compound 5i) is a selective dopamine D3 receptor and 5-HT2A receptor antagonist and a partial 5-HT1A receptor agonist. D3/5-HT receptor modulator-1 shows Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for dopamine D3, 5-HT2A, and 5-HT2A receptors. D3/5-HT receptor modulator-1 has a low affinity for dopamine D2 receptors, 5-HT2C receptors, and hERG channels. D3/5-HT receptor modulator-1 has an atypical antipsychotic profile. | ||||||||||||||||||||
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Keywords
