915289-61-1
Chemical Structure
Bakkenolide Iva
- CAS No.: 915289-61-1
- Formula:C24H32O6S
- Molecular Weight:448.57
IUPAC Name: (1'R,3R,3a'R,4'S,7'S,7a'R)-3a',4'-dimethyl-4-methylene-7'-(((E)-3-(methylthio)acryloyl)oxy)-2-oxodecahydro-2H-spiro[furan-3,2'-inden]-1'-yl 3-methylbut-2-enoate
InChIKey: ZLHYWYGFBCIFEG-AWYFUHEJSA-N
SMILES: O(C(C=C(C)C)=O)[C@H]1[C@@]2(C[C@@]3(C)[C@@]1([C@@H](OC(C=CSC)=O)CC[C@@H]3C)[H])C(=C)COC2=O
Biological Activity: Bakkenolide Iva is a bakkenolide-type sesquiterpene. Bakkenolide Iva is isolated from the rhizomes of Petasites tricholobus. Bakkenolide Iva inhibits lipid peroxidation in rat brain homogenates and scavenges DPPH free radicals. Bakkenolide Iva protects cortical neurons against oxygen-glucose deprivation-induced injury and oxidative stress-induced neuronal injury. Bakkenolide Iva can be used in research on paralysis and allergic rhinitis[1][2][3].
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Bakkenolide Iva | Bakkenolide Iva is a bakkenolide-type sesquiterpene. Bakkenolide Iva is isolated from the rhizomes of Petasites tricholobus. Bakkenolide Iva inhibits lipid peroxidation in rat brain homogenates and scavenges DPPH free radicals. Bakkenolide Iva protects cortical neurons against oxygen-glucose deprivation-induced injury and oxidative stress-induced neuronal injury. Bakkenolide Iva can be used in research on paralysis and allergic rhinitis. | |||||||||||||||||||||
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References
- [1]. Wang YL, et al. Bakkenolides from Petasites tricholobus and their neuroprotective effects related to antioxidant activities. Planta medica. 2009 Feb;75(3):230-5. [Content Brief]
- [2]. van der Meer JW, et al. Abstract!. The Netherlands journal of medicine. 2002 Dec;60(11):418. [Content Brief]
- [3]. Zhang FJ, et al. Anti-allergic effects of total bakkenolides from Petasites tricholobus in ovalbumin-sensitized rats. Phytotherapy research : PTR. 2011 Jan;25(1):116-21. [Content Brief]
