939825-12-4
939825-12-4
Chemical Structure
OB-24
- CAS No.: 939825-12-4
- Formula:C15H18BrClN2O2
- Molecular Weight:373.67
IUPAC Name: 1-((2-(4-bromophenethyl)-1,3-dioxolan-2-yl)methyl)-1H-imidazole hydrochloride
InChIKey: YSOWYXRHOAXXTG-UHFFFAOYSA-N
SMILES: BrC1=CC=C(CCC2(CN3C=CN=C3)OCCO2)C=C1.Cl
Biological Activity: OB-24 is a selective small-molecule HO-1 inhibitor (IC50 = 1.9 μM for HO-1 and IC50 for HO-2 >100 μM). OB-24 possesses anti-tumor and anti-metastatic properties. OB-24 can be studies in research such as prostate cancer, melanoma, ovarian carcinoma and lung metastasis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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OB-24 | 98.21% | OB-24 is a selective small-molecule HO-1 inhibitor (IC50 = 1.9 μM for HO-1 and IC50 for HO-2 >100 μM). OB-24 possesses anti-tumor and anti-metastatic properties. OB-24 can be studies in research such as prostate cancer, melanoma, ovarian carcinoma and lung metastasis. | ||||||||||||||||||||
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References
- [1]. Alaoui-Jamali MA, et al. A novel experimental heme oxygenase-1-targeted therapy for hormone-refractory prostate cancer. Cancer Res. 2009;69(20):8017-8024. [Content Brief]
- [2]. Moulay. Alaoui-Jamali, et al., OB-24, a novel selective and potent HO-1 inhibitor, induces a wide spectrum anti-tumor activity in vitro and in vivo and synergizes with chemotherapy drugs. Mol Cancer Ther 1 November 2007; 6 (11_Supplement): C82.
Keywords
