944328-88-5
944328-88-5
Chemical Structure
QS11
- CAS No.: 944328-88-5
- Formula:C36H33N5O2
- Molecular Weight:567.68
IUPAC Name: (S)-2-((9-([1,1'-biphenyl]-4-ylmethyl)-2-((2,3-dihydro-1H-inden-5-yl)oxy)-9H-purin-6-yl)amino)-3-phenylpropan-1-ol
InChIKey: DOKZLKDGUQWMSX-HKBQPEDESA-N
SMILES: OC[C@H](CC1=CC=CC=C1)NC2=C3C(N(CC4=CC=C(C5=CC=CC=C5)C=C4)C=N3)=NC(OC6=CC=C(CCC7)C7=C6)=N2
Biological Activity: QS11 is an inhibitor of ARFGAP1 (ADP-ribosylation factor GTPase-activating protein 1), with an EC50 of 1.5 μM. QS11 activates Wnt/β-catenin signaling through an effect on protein trafficking. QS11 inhibits migration of ARFGAP overexpressing breast cancer cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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QS11 | 99.10% | QS11 is an inhibitor of ARFGAP1 (ADP-ribosylation factor GTPase-activating protein 1), with an EC50 of 1.5 μM. QS11 activates Wnt/β-catenin signaling through an effect on protein trafficking. QS11 inhibits migration of ARFGAP overexpressing breast cancer cells. | ||||||||||||||||||||
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