946396-92-5
Chemical Structure
HSD-016
- CAS No.: 946396-92-5
- Formula:C21H21F7N2O3S
- Molecular Weight:514.46
IUPAC Name: (R)-1,1,1-trifluoro-2-(3-(((R)-4-(4-fluoro-2-(trifluoromethyl)phenyl)-2-methylpiperazin-1-yl)sulfonyl)phenyl)propan-2-ol
InChIKey: ZWASRJHIEFYJGL-BFUOFWGJSA-N
SMILES: FC(C1=C(C=CC(F)=C1)N2C[C@@H](C)N(CC2)S(=O)(C3=CC([C@@](O)(C(F)(F)F)C)=CC=C3)=O)(F)F
Biological Activity: HSD-016 is a potent, selective and orally active 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with IC50 values of 11, 1 and 8 nM against human, mouse and rat 11β-HSD1, respectively. HSD-016 can be used for type 2 diabetes research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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HSD-016 | 99.95% | HSD-016 is a potent, selective and orally active 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with IC50 values of 11, 1 and 8 nM against human, mouse and rat 11β-HSD1, respectively. HSD-016 can be used for type 2 diabetes research. | ||||||||||||||||||||
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Keywords
