Cbz-Gly-Pro-Ala-O-cinnamyl
Cbz-Gly-Pro-Ala-O-cinnamyl (compound 25) is a small peptide targeting BACE-1 and AChE with the IC50 values of 0.02 μM and 1 μM, respectively. Cbz-Gly-Pro-Ala-O-cinnamyl shows neuroprotective effect and can be used for study of Alzheimer’s disease.
For research use only. We do not sell to patients.
- Formula: C27H31N3O6
- Molecular Weight:493.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
Cbz-Gly-Pro-Ala-O-cinnamyl (compound 25) (10 μM, 48 h) exhibites 54% inhibition of Aβ1–42 aggregation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Scopolamine (HY-N0296)-affected memory impairment in mice[1]
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Dosage:10 mg/kg
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Administration:i.p. for 9 days
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Result:Reversed Scopolamine (HY-N0296)-affected memory impairment.
Chemical Information
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Molecular Weight 493.55
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Formula C27H31N3O6
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SMILES
O=C(NCC(N1[C@@H](CCC1)C(N[C@H](C(OC/C=C/C2=CC=CC=C2)=O)C)=O)=O)OCC3=CC=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cbz-Gly-Pro-Ala-O-cinnamyl Related Classifications
HY-163382 Related Classifications
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