2. Metabolic Enzyme/Protease
  3. Tyrosinase Endogenous Metabolite
  4. Cepharadione B

Cepharadione B (compound 22) is a natural compound isolated from the leaves of Piper sanctum. Cepharadione B is a tyrosinase inhibitor with an IC50 value of 170 μM, and inhibits cell growth in A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT-15 cells.

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Cepharadione B

Cepharadione B Estructura química

No. CAS : 55610-02-1

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Cepharadione B Related Antibodies

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Descripciòn

Cepharadione B (compound 22) is a natural compound isolated from the leaves of Piper sanctum. Cepharadione B is a tyrosinase inhibitor with an IC50 value of 170 μM, and inhibits cell growth in A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT-15 cells[1][2][3].

Cellular Effect
Cell Line Type Value Description References
BXPC-3 GI50
> 10 μg/mL
Compound: 1
Growth inhibition of human BXPC3 cells after 48 hrs by SRB assay
Growth inhibition of human BXPC3 cells after 48 hrs by SRB assay
[PMID: 17624787]
DU-145 GI50
36.1 μg/mL
Compound: 1
Growth inhibition of human DU145 cells after 48 hrs by SRB assay
Growth inhibition of human DU145 cells after 48 hrs by SRB assay
[PMID: 17624787]
KM-20L2 GI50
> 10 μg/mL
Compound: 1
Growth inhibition of human KM20L2 cells after 48 hrs by SRB assay
Growth inhibition of human KM20L2 cells after 48 hrs by SRB assay
[PMID: 17624787]
MCF7 GI50
> 10 μg/mL
Compound: 1
Growth inhibition of human MCF7 cells after 48 hrs by SRB assay
Growth inhibition of human MCF7 cells after 48 hrs by SRB assay
[PMID: 17624787]
NCI-H460 GI50
> 10 μg/mL
Compound: 1
Growth inhibition of human NCI-H460 cells after 48 hrs by SRB assay
Growth inhibition of human NCI-H460 cells after 48 hrs by SRB assay
[PMID: 17624787]
SF-268 GI50
22.8 μg/mL
Compound: 1
Growth inhibition of human SF268 cells after 48 hrs by SRB assay
Growth inhibition of human SF268 cells after 48 hrs by SRB assay
[PMID: 17624787]
Peso molecular

321.33

Fòrmula

C19H15NO4
No. CAS
SMILES

O=C1C(N(C)C2=C3C1=CC(OC)=C(OC)C3=C4C(C=CC=C4)=C2)=O
Structure Classification
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
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Cepharadione B Related Classifications

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Keywords:

Cepharadione B55610-02-1TyrosinaseEndogenous MetaboliteCepharadione B (compound 22) 是从胡椒叶中分离得到的天然化合物。Cepharadione B 是一种 tyrosinase 抑制剂，其 < B >IC50值为170 μM抑制 A-549、SK-OV-3、SK-MEL-2、XF-498 和 HCT-15 细胞的生长。Inhibitorinhibitorinhibit

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