CGP 20712 dihydrochloride
Based on 1 Customer Validation
CGP 20712 dihydrochloride is a highly selective β1-adrenoceptor antagonist with an IC50 of 0.7 nM. CGP 20712 dihydrochloride exhibits ~10,000-fold selectivity over β2-adrenoceptors.
For research use only. We do not sell to patients.
- Purity: 99.4%
- CAS No.: 1216905-73-5
- Formula: C23H27Cl2F3N4O5
- Molecular Weight:567.39
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 1216905-73-5
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Appearance Solid
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Molecular Weight 567.39
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Formula C23H27Cl2F3N4O5
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Color White to light yellow
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SMILES
O=C(N)C1=CC(OCCNCC(O)COC2=CC=C(C3=NC(C(F)(F)F)=CN3C)C=C2)=CC=C1O.Cl.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 28 mg/mL (49.35 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Kitagawa Y, et al. Determination of beta-adrenoceptor subtype on rat isolated ventricular myocytes by use of highly selective beta-antagonists. Br J Pharmacol. 1995 Sep;116(1):1635-43. [Content Brief]
[2]. Dooley DJ, et al. CGP 20712 A: a useful tool for quantitating beta 1- and beta 2-adrenoceptors. Eur J Pharmacol. 1986 Oct 14;130(1-2):137-9. [Content Brief]
[3]. Kitagawa Y, et al. Determination of beta-adrenoceptor subtype on rat isolated ventricular myocytes by use of highly selective beta-antagonists. Br J Pharmacol. 1995 Sep;116(1):1635-43. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7625 mL | 8.8123 mL | 17.6246 mL | 44.0614 mL |
| 5 mM | 0.3525 mL | 1.7625 mL | 3.5249 mL | 8.8123 mL | |
| 10 mM | 0.1762 mL | 0.8812 mL | 1.7625 mL | 4.4061 mL | |
| 15 mM | 0.1175 mL | 0.5875 mL | 1.1750 mL | 2.9374 mL | |
| 20 mM | 0.0881 mL | 0.4406 mL | 0.8812 mL | 2.2031 mL | |
| 25 mM | 0.0705 mL | 0.3525 mL | 0.7050 mL | 1.7625 mL | |
| 30 mM | 0.0587 mL | 0.2937 mL | 0.5875 mL | 1.4687 mL | |
| 40 mM | 0.0441 mL | 0.2203 mL | 0.4406 mL | 1.1015 mL |
CGP 20712 dihydrochloride Related Classifications
HY-101355A Related Classifications
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