P-8977
P-8977 is a potent dual CO/5-LO inhibitor (IC50 = 0.01 µM). P-8977 can also inhibit cyclooxygenase (CO) (IC50 = 0.53 µM) in 3T3 cells. P-8977 can inhibit ear edema. P-8977 can be used for research on inflammatory skin conditions.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 135810-00-3
- Formel: C18H17NO4
- Molecular Weight:311.33
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RBL-1 | IC50 |
0.01 μM
Compound: 24h
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Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatant
Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatant
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[PMID: 8568814] |
Chemical Information
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CAS. Nr. 135810-00-3
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Molecular Weight 311.33
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Formel C18H17NO4
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SMILES
O=C1C2=C(COC3=CC=C(CCC(N(C)O)=O)C=C13)C=CC=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
P-8977 Related Classifications
HY-108109 Related Classifications
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