135810-00-3
135810-00-3
Chemical Structure
P-8977
- CAS No.: 135810-00-3
- Formula:C18H17NO4
- Molecular Weight:311.33
IUPAC Name: N-hydroxy-N-methyl-3-(11-oxo-6,11-dihydrodibenzo[b,e]oxepin-2-yl)propanamide
InChIKey: JBBIBEHATNQSPR-UHFFFAOYSA-N
SMILES: O=C1C2=C(COC3=CC=C(CCC(N(C)O)=O)C=C13)C=CC=C2
Biological Activity: P-8977 is a potent dual CO/5-LO inhibitor (IC50 = 0.01 µM). P-8977 can also inhibit cyclooxygenase (CO) (IC50 = 0.53 µM) in 3T3 cells. P-8977 can inhibit ear edema. P-8977 can be used for research on inflammatory skin conditions[1].
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P-8977 | P-8977 is a potent dual CO/5-LO inhibitor (IC50 = 0.01 µM). P-8977 can also inhibit cyclooxygenase (CO) (IC50 = 0.53 µM) in 3T3 cells. P-8977 can inhibit ear edema. P-8977 can be used for research on inflammatory skin conditions. | |||||||||||||||||||||
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