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2991054-23-8

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2991054-23-8" in MCE Product Catalog:

Art. -Nr.: HY-155195
CAS. Nr.: 2991054-23-8
Reinheit:  98.00%
Target:  

FLT3

Forschungsgebiete:  

Cancer

FLT3/CHK-IN-1 (Compound 18) is a dual inhibitor of FLT3/CHK1. FLT3/CHK-IN-1 is more than 1700 times more selective to c-KI T and greatly reduces hERG affinity with an IC50 value of 58.4 μM. FLT3/CHK-IN-1 inhibits tumor growth in mouse xenotransplantation models inoculated with MV-4-11 cells .
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